Clonazepam 2mg vs xanax 3mg, N = 12
Psychiatric buy clonazepam online uk State
Psychiatric symptoms improved to mild disability
Labs tested for serotonin transporter and dopamine D2 receptor in liver, adrenals, brain blood flow
The two drugs had an opposite effect in the liver; clonazepam improved mood, whereas xanax worsened it.
Psychiatrist: "There's probably something going on in the brain, and I'm not sure how much."
Results of Laboratory Tests
Mean concentration of 5-HT and D2 receptors (5-HTTLPR) at baseline
Clonazepam
Clonazepam increased 5-HT transporter levels 4-fold
D2 receptor increased 2.4-fold
D2 receptor decreased by 2.2-fold
xanax
xanax had a similar online pharmacy adderall with prescription effect to clonazepam.
Psychiatric Symptoms
The two drugs improved both mental and physical state whereas xanax worsened the mental state more
The study was not able to establish whether or not xanax is a serotonin/dopamine reuptake inhibitor.
Discussion
The study results may be interpreted as showing that there is both an antagonist and agent that stimulates the serotonin/dopamine reuptake. However, they may not, or only partially.
Both 5-HT and D2 receptors are involved in reuptake of serotonin. 5-HTTLPR is a gene that Buy clonazepam uk has direct effect on both its formation and stability.
Clonazepam antagonizes the reuptake of serotonin, whereas xanax induces reuptake.
The only way to get a truly detailed breakdown of the effects both drugs would be to measure levels of all 5-HT and D2 receptors other markers. The results can be extrapolated to serotonin/dopamine reuptake inhibitors.
Sources
Wendt, D. M., Dziedzic, B.M., Clonazepam tab 2mg & Pichlow, D. J. (2015). Effects of clonazepam and xanax on subjective physiologic effects of serotonin and dopamine reuptake inhibitors. Clinical Neuropharmacology, doi:10.1002/cnp.3158
Treatment-emergent Serotonin-Dopamine Neuroleptic Malignant Syndrome.
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